Tabelle 4.
Clinical and biochemical characteristics of population divided according to pre-HD and delta OER value. Data are M ± SE.
| Patients, (n.) | Pre-HD OER | p< | Delta OER | p< | ||
|---|---|---|---|---|---|---|
| OER ≤ 32% (15) | OER > 32% (15) | Delta OER ≥ 40% (14) | Delta OER ≤ 40% (16) | |||
| Men/Females; n (%) | 8 (53)/7 (47) | 5 (33)/10 (66) | 7 (50)/7(50) | 6 (37)/10 (63) | ||
| Age, yr | 76 ± 3.0 | 73 ± 3.4 | n.s | 75 ± 3 | 76 ± 3 | n.s |
| Vintage HD, yr | 3.0 ± 0.7 | 4.0 ± 0.6 | n.s | 3.0 ± 0.7 | 3.5 ± 0.6 | n.s |
| Comorbidities; n (%) | 7 (46) | 8 (53) | n.s | 6 (42) | 9 (68) | n.s |
| - Obesity (BMI > 30) | 0 | 3 (20) | 1 (7) | 2 (12) | ||
| -Diabetes, n (%) | 7 (46) | 4 (26) | 7 (50) | 4 (25) | ||
| - Vascular co-morbidities* | 3 (20) | 5 (33) | 4 (28) | 4 (25) | ||
| Follow-up, months, (range) | 12 ± 2.2 (23–3) | 19 ± 1.1 (23–3) | n.s | 14 ± 1,6 (21–3) | 16 ± 2 (23–3) | n.s |
| All-cause mortality, n (%) | 10 (67) | 3 (20) | 0.01 | 9 (64) | 4 (25) | 0.01 |
| - Infection | 3 (20) | 1 (7) | 3 (33) | 1 (25) | ||
| - Acute coronary syndrome | 3 (20) | 0 | 2 (22) | 1 (25) | ||
| - Neoplasia | 2 (13) | 1 (7) | 2 (22) | 1 (25) | ||
| - Protein energy wasting | 2 (13) | 1 (7) | 2 (22) | 1 (25) | ||
| OER first measurement, % | 27 ± 0.8 | 37 ± 1.3 | 0.001 | 29 ± 1 | 36 ± 2 | 0.001 |
| Delta OER, % | 48 ± 5.2 | 33 ± 4.7 | 0.04 | 59 ± 2 | 24 ± 2 | 0.001 |
| OER LOCF#, % | 34 ± 2.2** | 38 ± 1.7 | n.s | 37 ± 2.4** | 35.0 ± 1.6 | n.s |
(*)Vascular co-morbidities = Peripheral ischemia and acute Coronary Syndrome§; (#)LOCF: last observation carried forward.
All comparisons are t-test, except for X2 test (#) applied for comorbidities and mortality.
(**)p < 0.01 vs OER first measurement.