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. 2018 Mar 29;9:301. doi: 10.3389/fphar.2018.00301

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Copyright © 2018 Wang, Dai, Song, Zhu, Liu, Hou, Ke, Zhou, Qiu, Wang, Jiang, Jia and Feng.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Effects of LLC on autophagy in the hearts from rats subjected to myocardial ischemia injury. (A) Representative transmission electron ultra-images showing autophagic vacuoles (marked with red arrows in the images, scale bar = 0.5 μm). (B) Quantitative analysis of the number of autophagic vacuoles in (A). (C) Expression levels of LC3, Beclin 1 and p62 changes with LLC (80 mg⋅Kg^-1) pretreatment. Data were presented as means ± SD. ^∗∗P < 0.01 vs. Con group, ^#P < 0.05, ^##P < 0.01 vs. ISO group.