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. 2018 Mar 29;9:588. doi: 10.3389/fimmu.2018.00588

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Copyright © 2018 Serwas, Huemer, Dieckmann, Mejstrikova, Garncarz, Litzman, Hoeger, Zapletal, Janda, Bennett, Kain, Kerjaschky and Boztug.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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mRNA expression of several granule proteins in neutrophils of specific granule deficiency patients is reduced. (A–G) Transcript analysis of LTF (A), LCN2 (B), ALOX15 (C), OLF4 (D), VIM (E), SYNE2 (F), and MYO18A (G) on neutrophils of both patients (P1 and P2) and two healthy controls (HC1, shipment control; HC2, local control, three biological replicates shown). Gene expression was normalized to HPRT1 expression. Significance levels were determined with one-way ANOVA (Bonferroni corrected for multiple testing).