Table 2.

Significance of mean differences between the years concerning the factors studied

Tests of differences between years	2010 vs. 2005	2015 vs. 2010	2015 vs. 2005
Age, mean difference in years (p value, t test)	0.94 (0.260)	− 1.20 (0.206)	− 0.27 (0.777)
Proportion of females, difference in %, (p value, PR test)	0.018 (0.762)	− 0.042 (0.489)	− 0.023 (0.689)
Length of care episode, mean difference in days (p value, t test)	− 1.44 (0.848)	− 0.92 (0.160)	− 2.35 (0.003)*
Comorbidity (p value, Wilcoxon’s rank sum-test, z)	1.51 (0.130)	2.40 (0.016)*	4.09 (< 0.001)*
Number of drugs at admission, mean difference (p value, t test)	1.87 (< 0.001)*	0.56 (0.259)	2.43 (< 0.001)*
Number of drugs at discharge, mean difference (p value, t test)	1.63 (0.001)*	0.85 (0.086)	2.48 (< 0.001)*
Drug changes, mean difference (p value, t test)	0.26 (0.2140)	− 1.03 (< 0.001)*	− 0.78 (< 0.001)*
IDU index, mean difference (p value, Wilcoxon’s rank sum-test, z)	− 2.79 (0.005)*	4.29 (< 0.001)*	1.70 (0.088)

Data are presented as mean ± standard deviation unless otherwise indicated

IDU inappropriate drug use

*p < 0.05