Table 2.

Characteristics of the included studies and the enrolled patients

Name, year	Hypotensive subjects (N)	Age range (mean)	Site	Location	Study type	Blood pressure and injury score
						SBP (mmHg)	ISS
Bickell et al. [13]	598	20–40 (31)* years	Emergency department	Houston, USA	Randomised control trial	75.5**	26*
Dutton et al. [26]	110	17–42 (31)* years	Emergency department	Maryland, USA	Randomised control trial	107**	21.73**
Talving et al. [32]	102	22–55 (35.5)** years	Pre-hospital	Stockholm, Sweden	Retrospective (non-comparative)	U/S	28.5**
Morrison et al. [27]	90	15–45 (32.3)** years	Operating room	Houston, USA	Randomised control trial	75.85**	19.1**
Ley et al. [33]	Overall: 3137 H: 106	20–69 (37)* years	Emergency department	California, USA	Retrospective (non-comparative)	Overall: 133*	Overall: 10.3*
Kasotakis et al. [30]	1754	16–90 (43.5)* years	In-hospital	Multi-trauma centres, USA	Prospective (non-comparative)	111.1*	32.2*
Brown et al. [31]	Overall: 1216 H: 616	19–89 (40)* years	Pre-hospital	Multi-trauma centres: USA	Prospective (comparative)	68**	41*
Schreiber et al. [28]	192	≥ 15 years (41)* years	Pre-hospital	Multi-trauma centres: United States and Canada	Randomised control trial	82.7**	32.5**
Geeraedts et al. [34]	941	≥ 16 years	Pre-hospital	Sydney, Australia	Retrospective (non-comparative)	81*	13**
Carrick et al. [29]	168	15–45 (30)* years	Operating room	Houston, USA	Randomised control trial	82**	17.5**

SBP systolic blood pressure, ISS injury severity score, U/S unspecified, *mean, **median