Table 4.
Pooled mortality rate between hypotensive and aggressive resuscitation groups in the comparative studies
| Name, year | Sample size of hypotensive patients | No of deaths | P value | Hazard ratio | Survival rate between restrictive versus large volume resuscitation (%) | |
|---|---|---|---|---|---|---|
| Death/patients (hypotensive group) (%) | Death/patients (aggressive group) (%) | |||||
| Randomised control trials and prospective study | ||||||
| Bickell et al. [13] | 598 | 86/289 (29.7) | 116/309 (37.5) | 0.04 | N/M | 70 versus 62 |
| Dutton et al. [26] | 110 | 4/55 (7.2) | 4/55 (7.2) | N/M | HR 1.00 | 92.7 versus 92.7 |
| Morrison et al. [27] | 90 | 10/44 (22.7) | 13/46 (28.2) | 0.58 | HR 1.10 | 77.2 versus 71.7 |
| Schreiber et al. [28] | 191 | 5/96 (5.2) | 14/95 (14.7) | N/M | aOR 0.39 | 94.8 versus 85.2 |
| Carrick et al. [29] | 168 | 18/86 (20.9) | 21/82 (25.6) | 0.47 | HR 0.48 | 78.5 versus 73.7 |
| Total | 1157 | 123/570 (21.57%) | 168/587 (28.6%) | |||
| Prospective cohort study | ||||||
| Brown et al. [31] | 603 | 19/123 (15.4%) | 18/480 (3.75) | 0.90 | HR 0.81 | 84.55 versus 96.25 |
| Groups | Population (n) | Mortality n (%) | Survival rate (mean) |
|---|---|---|---|
| Calculation of overall mortality rate and survival rate | |||
| Hypotensive resuscitation | 693 | 142 (20.49) | 82.95% |
| Aggressive resuscitation | 1067 | 186 (17.43) | 80.25% |
aOR adjusted odds ratio, n number, vs. versus