Table 2.
Baseline laboratory test values of patients receiving postoperative HPβCD-diclofenac
| Laboratory parametera | Age group (years) | p valueb | ||
|---|---|---|---|---|
| < 65 | 65–74 | ≥ 75 | ||
| Albumin, g/L | 38.5 (6.1) [855] | 36.1 (5.4) [277] | 35.1 (5.1) [125] | < 0.0001 |
| Protein, g/L | 64.1 (8.9) [855] | 60.0 (8.4) [277] | 58.6 (8.2) [125] | < 0.0001 |
| Blood urea nitrogen, mmol/L | 5.0 (1.7) [855] | 6.2 (2.1) [277] | 6.7 (2.3) [125] | < 0.0001 |
| Creatinine, μmol/L | 76.9 (16.0) [855] | 83.6 (20.4) [277] | 84.9 (21.8) [125] | < 0.0001 |
| Alanine aminotransferase, IU/L | 24.0 (26.5) [855] | 20.5 (19.2) [277] | 15.9 (8.3) [125] | 0.0006 |
| Aspartate aminotransferase, IU/L | 24.8 (33.8) [855] | 25.4 (31.0) [277] | 22.4 (14.3) [125] | 0.6711 |
| Gamma glutamyltransferase, IU/L | 37.9 (64.0) [582] | 31.5 (41.0) [247] | 27.3 (25.7) [113] | 0.0934 |
| Alkaline phosphatase, IU/L | 72.9 (23.7) [855] | 69.5 (23.3) [277] | 68.1 (23.2) [125] | 0.0248 |
| Total bilirubin, μmol/L | 8.1 (5.3) [855] | 8.5 (5.0) [277] | 8.6 (4.7) [125] | 0.4346 |
| Hematocrit | 0.38 (0.05) [835] | 0.38 (0.05) [270] | 0.36 (0.04) [123] | < 0.0001 |
| Hemoglobin, g/L | 128.0 (17.2) [847] | 124.7 (16.4) [274] | 119.4 (15.2) [124] | < 0.0001 |
| Erythrocytes, × 1012/L | 4.3 (0.5) [847] | 4.1 (0.5) [274] | 3.9 (0.5) [124] | < 0.0001 |
| Platelets, × 109/L | 292.5 (80.0) [833] | 263.6 (80.3) [269] | 256.5 (71.0) [122] | < 0.0001 |
| Leukocytes, × 109/L | 8.9 (3.9) [835] | 8.5 (3.3) [270] | 8.2 (3.0) [123] | 0.0654 |
aAll values are mean (standard deviation) [n]
bComparison of the three age groups was via ANOVA