Fig. 3.

Ultrastructure of nervous tissue obtained from control and experimental rat brains 7 weeks after perinatal asphyxia performed in 7-day-old rat. a Corpus callosum of H-I rat: characteristic microvilli on the endothelium surface (red asterisk) and a macrophage cell residing in the blood vessel wall (green arrow) suggesting temporal interruption of blood-brain barrier. b Activated microglial cells (green arrow) with numerous lysosomes (asterisk), filled with hydrolytic enzymes, in the hippocampus of H-I rats. c Malformed myelin sheaths with splitting lamellae in striatum of injured rats. d The bridging vessel (green arrow) in H-I rats indicating the ongoing angiogenesis, conducive to processes of neurorestoration