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. 2018 Mar 29;9:300. doi: 10.3389/fphar.2018.00300

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Copyright © 2018 Zuo, Zhou, Xu, Li, Liu, Shi, Kang, Gao, Du, Sun and Zhang.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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(A) The PCA plot of QC and samples in positive ion mode, (B) The PCA plot of QC and samples in negative ion mode, (C) The scatter distribution plot in the first principal components in positive ion mode, (D) The scatter distribution plot in the first principal components in negative ion mode.