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. 2018 Mar 29;9:302. doi: 10.3389/fphys.2018.00302

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Copyright © 2018 Chen, Wang, Wang, Li, Ma, Wang, Sima and Xu.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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(A) Hematoxylin-eosin staining and (B) cell membrane staining of the silkworm fat body (FB). Bombyx mori larvae were treated and sampled as described in the Figure 1. CK, the control group; AM, animal model of hyperproteinemia. FBs were analyzed at 24, 48, and 192 h after hyperproteinemia was induced. N, normal nuclei; DN, dense nuclei, CM, cell membrane; Vac, vacuolation; CFB, FB cells; IS, intercellular space; SRd, start of FB remodeling; Rd, remodeling of FB; CRd, complete remodeling of FB. The bar = 5 μm.