Table 2. Clinical associations and genotypic profiles of Long–Evans rat GBS isolates.
| Case ID | Sex | Enrofloxacin in drinking water | Source | Serotype† | ST† | Resistance genes*† | Genes for Virulence Factors*†‡ | ||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| β-Haemolysin/cytolysin (cylE) | Hyaluronate lyase (hylB) | CAMP factor (cfa/cfb) | Laminin-binding protein (lmb) | C5a peptidase (scpB) | Pili [PI-1, PI-2a (pilA, pilB, pilC, srtC3, srtC4)] | Fg-binding surface proteins A and B (fbsA and B) | |||||||
| Case 1 | Female | Untreated | Cardiac | 1b | 12 | tet(M) | X | X | X | X | X | X | |
| Blood | 1b | 12 | tet(M) | X | X | X | X | X | X | ||||
| Case 2 | Female | Treated (1 day) | Cardiac | 1b | 12 | tet(M) | X | X | X | X | X | X | |
| Fetus | 1b | 12 | tet(M) | X | X | X | X | X | X | ||||
| Carrier H15-14 | Male | Untreated | Nares wash | V | 1 | tet(M), ermA | X | X | X | X | X | X | X |
| Carrier H15-11 | Male | Treated | Nares wash | 1b | 12 | tet(M) | X | X | X | X | X | X | |
| Carrier H15-16 | Male | Treated | Nares wash | 1b | 12 | tet(M) | X | X | X | X | X | X | |
ST, Sequence Type.
*Data from table obtained using ResFinder and Comprehensive Antimicrobial Resistance Database (CARD).
†Preliminary data described in [22].
‡Virulence Factor Database (VFDB).