Table 1.
Hematological parameters in patients with HbQ India trait and HbQ India-Beta thalassemia trait (BTT) compound heterozygous state
| Hematological parameters | HbQ India trait (n = 25)# |
HbQ India-BTT (n = 6)* |
||
|---|---|---|---|---|
| Range | Mean ± SD (95% CI) |
Range | Mean ± SD (95% CI) |
|
| Hemoglobin (g/dL) | 10.1–17.2 | 12.6 ± 1.7 (12.0–13.4) |
8.6–14.5 | 10.9 ± 2.2 (8.1–13.8) |
| RBC count (×106/µL) | 3.2–5.7 | 4.4 ± 0.6 (4.2–4.7) |
4.1–6.6 | 5.4 ± 0.9 (4.3–6.6) |
| HCT (%) | 30.9–47.3 | 37.4 ± 4.4 (35.6–39.5) |
24.3–46.9 | 34.5 ± 8.2 (24.3–44.7) |
| MCV (fL) | 76.8–95.2 | 84.7 ± 6.0 (82.2–87.4) |
58.5–70.5 | 62.9 ± 4.4 (57.4–68.6) |
| MCH (pg) | 23.5–33.6 | 28.7 ± 2.7 (27.6–29.9) |
18.8–21.8 | 20.1 ± 1.2 (18.6–21.6) |
| MCHC (g/dL) | 30.5–36.3 | 33.8 ± 1.7 (33.1–34.6) |
29.9–35.4 | 32.0 ± 2.1 (29.3–34.7) |
| Platelets (×103/µL) | 151.0–396.0 | 287.8 ± 76.2 (179.8–294.9) |
231–335 | 280 ± 45.3 (223.7–336.2) |
| TLC (×103/µL) | 5.7–13.7 | 9.3 ± 2.0 (6.7–12.4) |
5.7–11.6 | 9.6 ± 2.3 (8.4–10.3) |
| HbA (%) | 74.2–84.7 | 79.77 ± 2.21 (78.8–80.7) |
81.7–85.6 | 83.91 ± 1.41 (82.4–85.4) |
| HbF (%) | 0.0–1.3 | 0.45 ± 0.42 (0.3–0.6) |
0.6–4.7 | 2.21 ± 1.69 (0.4–3.4) |
| HbA2 (%) | 0.9–3.2 | 2.28 ± 0.64 (2.0–2.5) |
4.9–6.1 | 5.58 ± 0.48 (5.1–6.1) |
| HbQ India (%) | 13.6–24.4 | 17.49 ± 2.30 (16.5–18.4) |
7.4–9.0 | 8.28 ± 0.70 (7.5–9.0) |
CBC data was not available for 2 patients# and 1 patient*