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. 2018 Apr 5;5:18016. doi: 10.1038/hgv.2018.16

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Copyright © 2018 The Author(s)

This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/

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Schematic representation (three-dimensional molecular representation) of DNA polymerase gamma (POLG) side chain interactions within the local region and the T599E variant, as well as its effect on DNA enzymatic processes. DNA is shown with cyan carbons and POLG with gray carbons.