Table 3. Predictive values of ECG patterns for the diagnosis of indirect signs of pulmonary hypertension (right ventricular hypertrophy or right atrial enlargement) in patients with pulmonary hypertension from the PAPUCO registry.

ECG criterion	Sensitivity (%)		Specificity (%)		Positive predictive values (%)		Negative predictive values (%)
	RVH	RAE	RVH	RAE	RVH	RAE	RVH	RAE
QRS axis ≥ 100°	45.8	47.4	85.7	73.9	91.7	75.0	31.6	46.0
Extreme axis deviation (QRS > 190°)	8.3	7.9	100.0	95.7	100.0	75.0	24.2	38.6
R/S ratio in V1 > 1 or R in V1 > 7 mm	56.3	57.9	78.6	65.2	90.0	73.3	34.4	48.4
Definite right ventricular hypertrophy	37.5	42.1	92.9	87.0	94.7	84.2	30.2	47.6
• QRS axis ≥ +100°; and
• R/S ratio in V1 ≥ 1 or R in V1 > 7 mm
Right bundle branch block and QRS right-axis deviation (≥ 100°)	2.1	2.6	100.0	100.0	100.0	100.0	23.0	38.3
P > 2 mm in lead II or > 1.5 mm in lead V1/V2, unchanged duration	45.8	39.5	85.7	60.9	91.7	62.5	31.6	37.8

RVH, right ventricular hypertrophy; RAE, right atrial enlargement.