Table 1.
Alcoholic Cirrhosis (AC) | Total Alcoholic Hepatitis (AH) | Surviving Alcoholic Hepatitis (SV) | Nonsurviving Alcoholic Hepatitis (NS) | |
---|---|---|---|---|
n | 27 | 24 | 14 | 10 |
Age | 51 ± 2.2 | 44 ± 3* | 39 ± 3 | 51 ± 4 |
Sex (% male) | 66% | 56% | 57% | 60% |
AST (U/L) | 77 ± 12 | 115 ± 16 | 126 ± 24 | 99 ± 22 |
ALT (U/L) | 38 ± 8 | 47 ± 8 | 50 ± 10 | 43 ± 15 |
GDH (U/L) | 33 ± 11 | 40 ± 9 | 28 ± 11 | 55 ± 15 |
Bilirubin (mg/dl) | 3.3 ± 0.65 | 19.0 ± 2.2* | 15.7 ± 2.3* | 23.5 ± 4.0* |
Creatinine (mg/dl) | 1.2 ± 0.1 | 1.5 ± 0.2* | 1.3 ± 0.3 | 1.8 ± 0.3* |
INR | 1.5 ± 0.13 | 2.3 ± 0.2* | 2.3 ± 0.3* | 2.3 ± 0.2* |
WBC | 6.6 ± 0.5 | 10.6 ± 1.0* | 9.6 ± 1.4* | 11.9 ± 1.7* |
LDH (U/L) | 303 ± 34 | 509 ± 80 | 513 ± 85* | 503 ± 163 |
CK (U/L) | 153 ± 80 | 247 ± 102 | 244 ± 110 | 252 ± 204 |
ALP (U/L) | 53 ± 8 | 73 ± 16 | 67 ± 10 | 82 ± 36 |
ABIC score | 6.9 ± 0.3 | 8.2 ± 0.4* | 7.4 ± 0.5 | 9.3 ± 0.5*† |
MELD score | 15.3 ± 1.2 | 31.1 ± 1.6* | 29.1 ± 2.7* | 34.0 ± 2.1* |
30-Day mortality | 0% | 41.6% | 0% | 100% |
The ABIC score was calculated as in Dominguez and coworkers5, and the MELD score was calculated as in Sheth et al.42. ANOVA was used to compare all three groups (AC, SV, and NS), and a t-test (nonparametric or parametric as appropriate) was used to compare two groups (AC, AH or SV, NS).
*p < 0.05, AH versus AC; †p < 0.05, NS versus SV.