Table 2. Multivariate Competing-Risks Regression Analyses of Factors Associated With Biochemical Failure After Radical Prostatectomy and Postoperative Radiotherapy.
| Factor | PS-Matched Patient Cohort, SHR (95% CI)a |
P Value |
|---|---|---|
| ART vs ESRT | 0.34 (0.24-0.48) | <.001 |
| Age at surgery | 1.00 (0.98-1.02) | .65 |
| Year of surgery | 1.02 (0.99-1.05) | .24 |
| Pathological T stage | ||
| T2 | 1 [Reference] | |
| T3a | 1.14 (0.78-1.67) | .51 |
| T3b | 1.87 (1.20-2.92) | .005 |
| Surgical Gleason score | 2.06 (1.75-2.41) | <.001 |
| Surgical margin (±) | 1.29 (0.82-2.04) | .27 |
| Omitting nodal RT | 2.27 (1.33-3.87) | .003 |
| RT dose (Gy), prostate fossa | 0.96 (0.91-1.01) | .10 |
| Postoperative ADT | 0.30 (0.12-0.74) | .009 |
Abbreviations: ADT, androgen deprivation therapy; ART, adjuvant radiation therapy; ESRT, early-salvage radiation therapy; PS, propensity score; RT, radiation therapy; SHR, subhazard ratio.
a
Subhazard ratios are reported for a 1-unit increase in the continuous variables.