Table 3. Secondary Outcomes Associated With Time and Blood Pressurea.
| Time Intervalb | General Anesthesia (n = 65) | Conscious Sedation (n = 63) | P Value |
|---|---|---|---|
| Time from symptom onset to arrival at neurointerventional suite, median (IQR), min | 159 (122-230) | 145 (113-231) | .55 |
| Time from arrival at neurointerventional suite to groin puncture, median (IQR), min | 24 (20-27) | 15 (12-20) | <.001 |
| Time from onset to groin puncture, mean (SD), min | 202 (71) | 186 (72) | .22 |
| Time from imaging to groin puncture, median (IQR), min | 61 (48-73) | 54 (40-75) | .13 |
| Time from groin puncture to reperfusion, median (IQR), min | 34 (21-51)c | 29 (16-51)d | .27 |
| Time from onset to reperfusion, median (IQR), min | 212 (180-288)c | 216 (162-285)d | .63 |
| Patients with 20% MAP decrease, No. (%) | 57 (87.7) | 22 (34.9) | <.001 |
| Patients with MAP <70 mm Hg | |||
| No. (%) | 23 (35.4) | 10 (15.9) | .01 |
| Median time (IQR), min | 2 (1-5.5) | 6.5 (2-13) | .09 |
| Phenylephrine hydrochloride, median (IQR), mg | 2.2 (1.2-3.0) | 0.2 (0.0-1.0) | <.001 |
| Ephedrine sulfate, median (IQR), mg | 10 (0-10) | 0 | <.001 |
Abbreviations: IQR, interquartile range; MAP, mean arterial pressure.
a
Decreases in blood pressure levels were treated with vasopressors (ephedrine and phenylephrine) to maintain the levels within recommended limits (systolic blood pressure >140 mm Hg; MAP >70 mm Hg).
b
Time from onset to groin puncture was normally distributed. Other time intervals were not normally distributed.
c
For the 50 reperfused patients.
d
For the 38 reperfused patients.