Table 1. Characteristics of the Derivation and Validation Cohorts.
| Characteristic | Derivation Cohort (n = 1066) | Validation Cohort (n = 230) | ||||
|---|---|---|---|---|---|---|
| Original Dataa | Imputed Data Value | Original Dataa | Imputed Data Value | |||
| No. (%) | Missing, No. | No. (%) | Missing, No. | |||
| Age, mean (SD), y | 39.3 (13.7) | 0 | 39.3 (13.7) | 41.9 (13.8) | 0 | 41.9 (13.8) |
| Sex | ||||||
| Female | 548 (51.4) | 0 | 548 (51.4) | 122 (53.0) | 0 | 122 (53.0) |
| Male | 518 (48.6) | 0 | 518 (48.6) | 108 (47.0) | 0 | 108 (47.0) |
| Log(No. of CTG repeats), mean (SD) | 2.65 (0.36) | 117 | 2.66 (0.36) | NA | NA | NA |
| Diabetes | 72 (6.8) | 0 | 72 (6.8) | 15 (6.8) | 9 | 17 (7.5) |
| Dyslipidemia | 165 (15.5) | 0 | 165 (15.5) | NA | NA | NA |
| Hypertension | 67 (6.3) | 0 | 67 (6.3) | NA | NA | NA |
| Smoker | 181 (17.0) | 0 | 181 (17.0) | NA | NA | NA |
| Dysphagia | 193 (20.0) | 101 | 214 (20.1) | NA | NA | NA |
| Need for walking support | 43 (4.0) | 22 | 45 (4.2) | 34 (14.8) | 0 | 34 (14.8) |
| Heart rate, median (IQR), beats per min | 68 (60-77) | 33 | 68 (60-77) | 66 (60-75) | 10 | 66 (60-75) |
| Blood pressure, median (IQR), mm Hg | ||||||
| Systolic | 117 (109-127) | 62 | 117 (109-128) | 120 (110-130) | 18 | 120 (110-130) |
| Diastolic | 70 (63-75) | 63 | 70 (63-75) | NA | NA | NA |
| Atrial fibrillation | 56 (5.3) | 1 | 56 (5.3) | NA | NA | NA |
| First-degree atrioventricular block | 325 (31.3) | 29 | 335 (31.4) | 105 (46.1) | 2 | 106 (45.9) |
| Bundle-branch block | 186 (17.4) | 35 | 198 (18.5) | 71 (31.1) | 2 | 72 (31.3) |
| Left ventricular ejection fraction, median (IQR), % | 65 (60-67) | 66 | 65 (60-67) | NA | NA | NA |
| Predicted vital capacity, median (IQR), % | 83 (68-95) | 139 | 83 (68-95) | 78 (63-94) | 21 | 78 (63-94) |
Abbreviations: IQR, interquartile range; NA, not applicable.
a
Values presented are for nonmissing data for the original data set and averaged over all complete data sets for imputed data.