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. 2018 Feb 5;75(4):428–435. doi: 10.1001/jamaneurol.2017.4842

Figure 2. Treatment Response to Apheresis Therapy Stratified by Immunopathological Patterns.

Figure 2.

A, Functional response to apheresis therapy is presented as the percentage of patients successfully treated with apheresis treatment, stratified according to pathological patterns; differences between patterns 1 and 3 and between patterns 2 and 3 are significant (P = .03 and P < .001, respectively). B, The percentage of patients with lesion improvement, as established by magnetic resonance imaging is shown; the difference between patterns 2 and 3 is significant (P = .03). C, The percentage of patients with an Expanded Disability Status Scale (EDSS) score in response to apheresis therapy is shown; the difference between patterns 2 and 3 is significant (P = .003). D, The median reductions in EDSS score within 1 month after apheresis therapy in therapy responders with pattern 1 and 2 lesions are shown. Bars and boxes define the minimum, 25th quartile, 75th quartile, and maximum changes in scores. the dots represent individual patients. Data to evaluate MRI and/or EDSS response were omitted when patient data were incomplete.