Skip to main content
. 2018 Feb 5;75(4):428–435. doi: 10.1001/jamaneurol.2017.4842

Table 1. Demographic and Clinical Characteristics of Cohort at the Time of Plasma Exchange/Immunoadsorption Treatment.

Characteristic No. (%) P Value
All (n = 69) Pattern 1 (n = 16) Pattern 2 (n = 40) Pattern 3 (n = 13)
Age, y, mean (SD) 36.6 (13.3) 35.3 (13.1) 38.4 (13.9) 32.7 (11.3) .38
Female 46 (67) 10 (63) 30 (75) 6 (46) .14
Disease duration, y, median (range) 0.2 (0.0-18.0) 0.1 (0.0-17.0) 0.6 (0.0-18.0) 0.1 (0.0-16.0) .07
Disease course
Clinically isolated syndrome 28 (41) 8 (50) 11 (28) 9 (69) .02
Remitting-relapsing 36 (52) 7 (44) 26 (65) 3 (23) .02
Secondary progressive 5 (7) 1 (6) 3 (8) 1 (8) >.99
Expanded Disability Status Scale score
Score at baseline, median (range) 1.0 (0.0-8.5) 0.0 (0.0-6.5) 2.0 (0.0-8.5) 0.0 (0.0-8.5) .20
Score at index attack, median (range) 6.0 (2.0-9.5) 7.5 (3.5-9.5) 5.0 (2.0-9.5) 6.0 (3.0-9.0) .12
Immunoadsorption and plasma exchange treatment
Initiation delay, d, mean (SD) 25.4 (20.4) 16.3 (13.6) 26.5 (22.8) 33.2 (16.1) .07
Therapy with high-dose corticosteroids before initiation 63 (91) 13 (81) 37 (93) 13 (100) .19
Therapy with disease-modifying drugs in the 3 mo before initiation, No./Total No. (%) 17/67 (25) 5/15 (33) 11/39 (28) 1 (8) .25