Table 4. Untimely First-line Benzodiazepine and Other Clinical Outcomes^a.

Variable	Outcome Proportion, No. (%) (N = 218)	Univariate Analysis		Multivariate Analysis
		Received Untimely Treatment, No. (%)	P Value	AOR	SE (95% CI)	P Value
More than the median convulsive duration (2 h)	119 (54.6)	87 (73.1)	.02	2.6	0.8 (1.38-4.88)	.003
Decline in baseline function at hospital dischargeb	47 (21.6)	33 (70.2)	.49	1.8	0.7 (0.81-3.80)	.15
ICU stay more than the median duration (4 d)	112 (51.4)	73 (65.2)	.89	1.1	0.4 (0.61-2.09)	.66
Hypotension	64 (29.4)	49 (76.6)	.04	2.3	0.8 (1.16-4.63)	.02
Other medical complications	58 (26.6)	39 (67.2)	.87	1.2	0.4 (0.62-2.36)	.63

Abbreviations: AOR, adjusted odds ratio; ICU, intensive care unit; RCSE, refractory convulsive status epilepticus.

^aThe results of AORs for multivariable analysis using logistic regression models, with untimely first-line benzodiazepine treatment (≥10 minutes after seizure onset) as the predictor and different tertiary clinical outcomes. Each outcome was adjusted for age, structural etiology, febrile RCSE, no neurological history, generalized RCSE, continuous RCSE, and use of 5 or more ASMs.

^bNot able to do the same tasks as before at hospital discharge.