| Recommended Regimens for Adults* |
|
| Early Latent Syphilis |
|
Benzathine penicillin G 2.4 million units IM in a single dose |
| Late Latent Syphilis or Latent Syphilis of Unknown Duration |
|
Benzathine penicillin G 7.2 million units total, administered as 3 doses of 2.4 million units IM each at 1-week intervals |
|
|
*Recommendations for treating syphilis in persons with HIV infection and pregnant women are discussed elsewhere in this report (see Syphilis in Persons with HIV infection and Syphilis during Pregnancy). |