Table 6.
Allocation of cT1-T2 N0 patients based on their pathological N-status and CTSK protein expression
| pN status | Total | |||
|---|---|---|---|---|
| pN0 | pN+ | |||
| CTSK | ≤25 > 25 |
8 6 |
1 9 |
9 15 |
| Total | 14 | 10 | 24 | |
The value of CTSK protein expression in predicting occult metastasis (≤25 predicts pN0, > 25 predicts pN+) in cT1-T2 N0 patients is calculated as follows: sensitivity (9/9 + 1) × 100% = 90%; specificity (8 + 6) × 100% =57%; positive predictive value (9/6 + 9) × 100% = 60%; negative predictive value (8/8 + 1) × 100% = 89%