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Fig. 4. Confocal Laser Scanning Microscopy (CLSM) images and fluorescence intensity for miRNA-21 detection in MCF-7 (A), NHDF (B) and HeLa (C) cells incubated with CuS@mSiO2-Y (row one) and CuS@mSiO2-Y/ATP without or with 980 nm NIR-laser irradiation (row two and row three). The nucleus was stained blue with Hoechst, and the red fluorescence was due to Cy3. The scale bar is 25 μm.