Figure 1.

Cytomorphological spectrum of Fibrolamellar-HCC (FL-HCC). (a) Loose aggregates and many large discohesive tumor cells with a few benign hepatocytes. (b) Tumor cells with fibrous stromal fragments. (c) Cells have abundant eosinophilic cytoplasm, large central nucleus, huge nucleolus and nuclear pseudo inclusions. (d) Intracytoplasmic pale bodies, hyaline inclusions. (e) Multinucleated cell with intra and extracellular hyaline material along with bile pigment. (f) Cell block showing sheets of tumor cells with similar findings. (a, c, d, e: MGG stain; b, f: H and E stain; a, b: ×100; c, d, e: ×400; f, ×40)