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. Author manuscript; available in PMC: 2018 Apr 5.
Published in final edited form as: Nature. 2017 May 17;545(7655):482–486. doi: 10.1038/nature22365

Extended Data Figure 3. Anti-ZIKV NS1 antibodies did not neutralize ZIKV virions.

Extended Data Figure 3

We premixed two dilutions of murine ZIKV NS1 polyclonal antisera (1:100 and 1:1000) with purified ZIKV GZ01 infectious virions. The same amount of pre-immune sera served as a negative control. After a 30 min incubation, the infectivity of the "antibody-ZIKV virion" mixture was determined by plaque assay on Vero cells. The values in the graph represent the mean ± s.e.m. p values were determined by two-tailed Mann-Whitney test. The data were combined from 3 biological repeats. n.s., not significant.