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. 2018 Jan 4;4(3):335–341. doi: 10.1001/jamaoncol.2017.4510

Figure. Cumulative Risk of Breast-ALCL per Attained Age in 1 Million Women in the General Population and With Breast Implants.

Figure.

ALCL Indicates anaplastic large-cell lymphoma. Cumulative risk of breast-ALCL in the general female population was calculated using the number of breast-ALCL cases without breast implants from the Nationwide Network and Registry of Histo- and Cytopathology in the Netherlands, and the age-specific size of the female Dutch population from 1990 to 2016 per age category. Cumulative risk of breast-ALCL associated with breast implants was calculated using the number of breast-ALCL cases with breast implants and the cumulative number of women with breast implants in the Netherlands from 1965 to 2016 per age category.

aThe sensitivity analysis for cumulative risk of breast-ALCL in women with breast implants was calculated by multiplying the background incidence of breast-ALCL without implants in the general female population with the OR for breast-ALCL in women with breast implants from the case-control study.