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. 2018 Jan 3;3(3):242–246. doi: 10.1001/jamacardio.2017.4873

Figure 2. Alleviation of Left Ventricular Pressure Overload Associated With Changes in Circulating Levels of Long-Chain Acylcarnitines.

Figure 2.

Long-chain acylcarnitine levels decreased significantly within 24 hours of the alleviation of severe aortic stenosis via transcatheter aortic valve replacement. In specific, C16 decreased by 30.2% (P = 7.3 × 10-6), C18:1 by 42.7% (P = 3.7 × 10-8), C18:2 by 37.3% (P = 5.1 × 10-6), and C18 by 38.3% (P = 3.4 × 10-5). Kynurenine levels increased by 25.8% (P = 8.9 × 10-4). Levels of C26 and choline did not significantly change.