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. 2018 Jan 18;136(3):286–290. doi: 10.1001/jamaophthalmol.2017.6290

Table 2. Agreement and Differences in BCVA Letter Score: Number or Landolt C Charts vs Alphabet Charts.

ETDRS Chart Type Concordance Correlation Coefficient (95% CI)a Difference in Letter Scores (95% CI)b
Group A (20/20-20/25) Group B (20/20-20/40) Group C (20/50-20/100) Group D (20/125-20/200) Group A (20/20-20/25) Group B (20/20-20/40) Group C (20/50-20/100) Group D (20/125-20/200)
Number vs alphabet 0.89 (0.82 to 0.93) 0.97 (0.94 to 0.98) 0.92 (0.86 to 0.96) 0.96 (0.87 to 0.99) 1.16 (−2.98 to 5.29) 0.70 (−3.96 to 5.36) 0.94 (−6.17 to 8.05) 0.21 (−4.98 to 5.41)
Landolt C vs alphabet 0.72 (0.52 to 0.83) 0.83 (0.68 to 0.91) 0.79 (0.61 to 0.89) 0.89 (0.66 to 0.97) −4.80 (−13.5 to 3.91) −7.56 (−20.12 to 5.00) −8.04 (−21.33 to 5.26) −6.36 (−14.07 to 1.35)
P valuec .003 <.001 .01 .11 <.001 <.001 <.001 .001

Abbreviations: BCVA, best-corrected visual acuity; ETDRS, Early Treatment Diabetic Retinopathy Study.

a

Concordance correlation coefficients were calculated from intraclass correlation (interpretation: <0.40, poor; 0.40-0.59, fair; 0.60-0.74, good; and 0.75-1.00, excellent).

b

Negative sign indicated that the ETDRS letter scores were less than those measured with the alphabet chart.

c

P values for the differences in agreement (intraclass correlation coefficients) were calculated using the F test, and the P values for the differences in letter scores across charts were calculated using the Wilcoxon signed rank test.