Table 1. Summary of Study Characteristics.
| Reference | Country, publication year | Dates of data collection | Study design | Diagnosis* | No of cases | No of deaths | Age (range, mean, or percentage in years) | Percent male (%) |
|---|---|---|---|---|---|---|---|---|
| Studies included in meta-analysis | ||||||||
| Eisemann et al [44] | Germany, 2016 | 1997-2011 | Retrospective cohort using national registries | BCC | 380030 | 101848** | 68.9 | 50.8 |
| SCC | 92108 | 35185** | 75.6 | 58.1 | ||||
| Jensen et al 2008†† [25] | Denmark, 2008 | 1978-2001 | Retrospective cohort using national registries | BCC | 82837 | 28758 | 58.3% >65 | 48 |
| SCC | 13453 | 6998 | 78.3% >65 | 60.6 | ||||
| Rees et al [29] | USA, 2015 | 1993-2009 | Retrospective cohort from previous case-control study | BCC | 1363 | 169 | -- | 50.1 |
| SCC | 880 | 189 | 61.4 | |||||
| Hollestein et al [6] | Netherlands, 2012 | 1989-2008 | Retrospective cohort using national registries | SCC | 69408 | 31903 | 73.6 | 59.9 |
| Studies not included in meta-analysis | ||||||||
| Brondum-Jacobsen et al†† [27] | Denmark, 2013 | 1980-2006 | Retrospective cohort using national registries | KC | 129206 | -- | >40 | 49 |
| Clayman et al [47] | USA, 2005 | 1996-2001 | Prospective cohort | SCC | 210 | 52 | 34-94.7 | 89.1 |
| Jensen et al 2010†† [34] | Denmark, 2010 | 1990-2005 | Retrospective cohort using national registries | BCC | 72295 | -- | 8-106 | 47 |
| SCC | 11601 | -- | -- | 65 | ||||
| Kahn et al [28] | USA, 1998 | 1982-1994 | Prospective cohort | KC | 35062 | -- | M 61.5 (SD 9.1); F 60.5 (SD 10.1) | 54.5 |
| Karjalainen et al [23] | Finland, 1989 | 1967-1982 | Retrospective cohort using national registries | BCC | 23975 | -- | M=64.1; F=66.9. | 42.3 |
| SCC | 2927 | -- | M=68.5; F=72.0 | |||||
| Robsahm et al [39] | Norway, 2015 | 1963-2011 | Retrospective cohort using national registries | SCC | 30818 | -- | -- | 55.4 |
| Teppo et al [45] | Finland, 1999 | 1985-1994 | Retrospective cohort using national registries | SCC | -- | -- | -- | -- |
| Talback et al [46] | Sweden, 2004 | 1960-1998 | Retrospective cohort using national registries | SCC† | -- | -- | -- | -- |
*
BCC= basal cell carcinoma; SCC= squamous cell carcinoma; KC= keratinocyte carcinoma (BCC and SCC grouped together in publication)
**
Number of deaths was calculated using percentage of surviving patients presented in the article
†
Included ‘malignant skin cancer excluding melanoma’ in a cancer registry that does not collect BCC data
††
Jensen 2008, Brondum-Jacobsen, and Jensen 2010 have overlapping study populations. Brondum-Jacobsen was included qualitatively because it provides a combined BCC/SCC estimate. Jensen 2010 was included qualitatively because it adjusted extensively for covariates