Table 1.
Characteristics of ORALE Study Subjects with Rheumatoid Arthritis (RA)
| Variables | Mean ± SD or n, % | |
|---|---|---|
| Population | Mexican Americans (MAs) | European Americans (EAs) |
| No. of subjects phenotyped and genotypeda | 700 | 414 |
| Age (years) | 59.3 ± 11.3 | 64.4 ± 11.3 |
| Females | 79.0 % | 65.1 % |
| RA durationb (years) | 15.1 ± 10.3 | 16.7 ± 11.2 |
| IgM rheumatoid factor (RF) (IU/ml) | 765.5 ± 1643.7 | 410.6 ± 946.4 |
| IgM RF ≥ 25 (IU/ml)c | 637 (88.4%) | 333 (78.5%) |
| Anti-CCP (IU/ml)d | 390.2 ± 1468.3 | 252.7 ± 358.3 |
| Anti-CCP > 6.9 (IU/ml) | 597 (82.9%) | 319 (75.2%) |
| CIMTe | 0.98 ± 0.44 | 1.15 ± 0.59 |
| CIMTf | − 0.12 ± 0.92 | 0.17 ± 1.01 |
| Plaque | 53.2% | 64.2% |
a
After sample and SNP QC analyses, the phenotypic and genotypic (i.e., SNPs with MAF < 0.01 were excluded) data available for association analysis by ethnic group;
b
Rheumatoid Arthritis (RA) duration;
c
IgM RF = IgM rheumatoid factor (RF);
d
Anti-CCP = Anti-cyclic citrullinated peptide;
e
CIMT original values;
f
CIMT values were inverse-normalized for association analyses.