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. Author manuscript; available in PMC: 2019 Apr 1.
Published in final edited form as: Atherosclerosis. 2017 Nov 26;271:92–101. doi: 10.1016/j.atherosclerosis.2017.11.024

Table 3.

a. Genetic Variants Associated with Carotid IMT in European Americans (p < 1.0E-4)
Chr. SNP Position, bpa Gene/Nearest Gene Loc. A1b MAFc BETA SE Pf
15 rs1867148 73127038 PPCDC I C 0.44 −0.2804 0.06064 5.11E-06
13 rs323453 104232379 LOC728183/DAOA IG G 0.34 −0.2724 0.06346 2.23E-05
1 rs4846566 217797888 LOC728510/ZC3H11B IG T 0.01 −1.186 0.2777 2.46E-05
2 rs12987042 38518674 ARL6IP2/RPLPO-like IG A 0.36 −0.2608 0.0619 3.13E-05
15 rs6495122 72912698 CPLX3/ULK3 IG A 0.42 −0.2525 0.06149 4.90E-05
1 rs2645091 2214505 SKI I T 0.15 −0.3511 0.08741 7.07E-05
16 rs17821532 52504199 FTO I A 0.05 −0.7006 0.1751 7.58E-05
6 rs7742814 119185974 C6orf204/ASF1A IG G 0.36 0.2555 0.06462 9.09E-05
11 rs4387380 5824023 OR52E6/OR52E8 IG C 0.03 −0.8226 0.2085 9.45E-05
b. Genetic Variants Associated with Plaque in European Americans (p < 1.0E-4)
Chr. SNP Position, bpa Gene/Nearest Gene Loc A1b MAFc ORd 95% CIe Pf
12 rs515291 38689259 SLC2A13 I G 0.32 0.4987 0.36–0.69 3.09E-05
11 rs10501399 68979039 MYEOV/CCND1 IG T 0.09 0.2938 0.16–0.52 3.34E-05
15 rs692390 39274282 EXDL1 I A 0.19 0.4138 0.27–0.63 4.30E-05
5 rs6887230 148706339 GRPEL2 I G 0.30 2.02 1.4–2.8 5.61E-05
17 rs2070776 59361230 CD79B C (ns) T 0.33 0.5033 0.36–0.71 6.68E-05
16 rs3785233 7607511 A2BP1 I C 0.16 0.419 0.27–0.65 9.49E-05
6 rs10948573 50800310 TFAP2D I G 0.37 2.044 1.4–2.9 9.68E-05

Chr. = chromosome; SNP = single nucleotide polymorphism;

a

Based on NCBI Build36/130 (hg18); Loc = Location; I = Intron; IG = Intergenic;

b

A1 = minor allele;

c

MAF = minor allele frequency;

c

OR = Odds Ratio;

e

CI = Confidence Interval;

f

p values ranked from low to high.