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. Author manuscript; available in PMC: 2019 Apr 1.
Published in final edited form as: Atherosclerosis. 2017 Nov 26;271:92–101. doi: 10.1016/j.atherosclerosis.2017.11.024

Table 4.

Common Association Signals with CIMT and Plaque in both Mexican American and European Americans

Chr. SNP Location, bpa Gene/Nearest Gene Type Mexican Americans European Americans Combined p valuec
A1b MAF β-SNP (SE) p-value A1b MA F β-SNP (SE) p-value
15 chr15:73071294 73071294 RPP25/SCAMP5 IG A 0.02 −0.5279
(0.1834)
0.004133 A 0.02 −0.7115
(0.2012)
4.54×10−4 2.66×10−5
11 rs582037 125723080 DCPS/ST3GAL4 IG A 0.40 0.1308
(0.0386)
0.005611 A 0.33 0.234
(0.0648)
3.48×10−4 2.76 × 10−5
3 rs4839634 144619509 SLC9A9 I G 0.15 0.1592
(0.0633)
0.01215 G 0.14 0.3274
(0.0897)
2.96×10−4 4.87 × 10−5
Plaque OR (SE) OR (SE)
1 rs6694848 63276194 LOC199897/FOXD3 IG A 0.33 1.516
(0.1309)
0.001473 A 0.46 1.782
(0.1718)
7.69×10−4 1.66×10−5
3 rs9809344 135825448 KY I T 0.23 0.7201
(0.1428)
0.02147 T 0.39 0.5426
(0.1676)
2.64×10−4 7.41×10−5
13 rs7327080 22689882 SGCG I G 0.33 1.404
(0.1259)
0.007004 G 0.32 0.5607
(0.1774)
0.001111 9.93×10−5

Chr. = chromosome; SNP = single nucleotide polymorphism; MAF = minor allele frequency;

a

Based on National Center for Biotechnology Information (NCBI) Build36 (hg18);

b

A1 = minor allele;

c

combined p values ranked from low to high;