Comparison of ROC curves for prediction of PTB: 20+0–22+6/26+0–28+6 weeks ratios of RANTES (broken green), IL-1β (orange), quantitative FFN (continuous green), and CL (blue). The change in concentration of CVF RANTES between 20+0–22+6 and 26+0–28+6 weeks expressed as a ratio indicated the highest predictive capacity for spontaneous PTB. These comparisons were made for only those patients (term and preterm) that had values for all five biomarkers. (For interpretation of the references to colour in this figure legend, the reader is referred to the web version of this article.)
CL, ultrasound cervical length; FFN, fetal fibronectin.