Figure 1.

Uptake of exosomes from fibroblasts into gastric cancer cells. Exosomes were dyed with PKH26 (red), and the nuclei of cancer cells were dyed with DAPI. PKH26-labelled exosomes derived from CaF64 were distinctly observed in the membrane and cytoplasm of NUGC-3 cells and OCUM-12 cells, but were scarcely found in that of MKN45, FU97 and MKN74 cells. Exosomes derived from NF64 were not found in any cancer cell lines. PKH26-labelled exosomes from CaF65 were also observed in NUGC-3 cells and OCUM-12 cells, but exosomes from NF65 were scarcely found. A full colour version of this figure is available at the British Journal of Cancer journal online.