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. 2018 Jan 8;27(6):1015–1026. doi: 10.1093/hmg/ddy018

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© The Author(s) 2018. Published by Oxford University Press.

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com

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Figure 4. — LNA-ASOs inhibit CUG^exp foci in F35T (CUG 22/1500) and F45 (CUG 16/71) endothelial cell lines. (A) Effect of LNAs on inhibition of CUG^exp RNA foci in F35T cells. CM: non-complementary negative control duplex RNA; LC: LNA analog of CM. (B) Effect of LNAs on inhibition of CUG^exp foci in F45 cells. Error bars represent SEM. *P < 0.05; ** P < 0.01; *** P < 0.001 compared with control LC. At least one hundred cells were analyzed for each experiment.