Table 1.

List of the CFTR correctors with concentrations utilized in this study

CFF namea	Original name	Compoundb	IUPAC name	Concentration µM
C2	VRT-640c	C	2-{1-[4-(4-Chloro-benzensulfonyl)-piperazin-1-yl]-ethyl}-4-piperidin-1-yl-quinazoline	5
C3	VRT-325d	B	4-Cyclohexyloxy-2-{1-[4-(4-methoxy-benzensulfonyl)-piperazin-1-yl]-ethyl}-quinazoline	10
C5	corr 5ae	H	4, 5, 7-trimethyl-N-phenylquinolin-2-amine	15
C6	corr 5ce	I	N-(4-bromophenyl)-4-methylquinolin-2-amine	10
C9	KM11060f	F	7-chloro-4-(4-(4-chlorophenyl sulfonyl)piperazin-1-yl)quinoline	10
C4	corr 4ae	E	N-[2-(5-Chloro-2-methoxy-phenylamino)-4'-methyl-[4, 5']bithiazolyl-2'-yl]-benzamide	10
C13	corr 4ce	Q	N-(2-(3-acetylphenylamino)-4'-methyl-4, 5'-bithiazol-2'-yl)benzamide	5
C14	corr 4de	R	N-(2'-(2-methoxyphenylamino)-4-methyl-5, 5'-bithiazol-2-yl)benzamide	5
C17	15jfg	A	N-(2-(5-chloro-2-methoxyphenylamino)-4'-methyl-4, 5'-bithiazol-2'-yl)pivalamide	2
C15	corr 2be	S	N-phenyl-4-(4-vinylphenyl)thiazol-2-amine	15
	VX809h Lumacaftor	U	3 -(6-(I -(2, 2- difluorobenzo[d][l, 3]dioxol-5-yl) cyclopropanecarboxamido)-3-methylpyridin-2-yl)benzoic acid	6
	Glafeninei		2, 3-dihydroxypropyl 2-[(7-chloroquinolin-4-yl)amino]benzoate	10

^aName according to the list of the Cystic Fibrosis Foundation [https://www.cff.org/CFTR-Chemical-Compound.pdf].

^bName according to [WO2014086687].

^cWO2004111014 A.

^dUS20050059687 A1.

^ePedemonte et al. (2005) (15).

^fRobert et al. (2008) (20).

^gYoo et al. (2008) (21).

^hUS2011257223.

ⁱRobert et al. (2010) (22).