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. 2017 Aug 21;26(22):4395–4405. doi: 10.1093/hmg/ddx325

Figure 6.

Figure 6.

Analysis of hepatic Akt and FGF21 in 60–78-week-old wild-type and rAAV-treated G6pt−/− mice. For quantitative RT-PCR, the data represent the mean ± SEM for 60–78-week-old wild-type (n = 30), G6PT/44–62% (n = 6), and G6PT/3–22% (GPE-low, n = 9 and miGT, n = 15) mice. (A) Quantification of mRNA for Akt, Western blot analysis of Akt, p-Akt-S473, p-Akt-T308, and β-actin and quantification protein levels by densitometry of wild-type (+/+, n = 17), G6PT/44–62% (n = 5), and G6PT/3–22% (n = 12) mice. (B) Quantification of mRNA for FGF21, Western blot analysis of FGF21, β-actin and quantification protein levels by densitometry of wild-type (+/+, n = 17), G6PT/44–62% (n = 5), and G6PT/3–22% (n = 12) mice. Data represent the mean ± SEM. *P < 0.05, **P < 0.005.