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Mislocalization of Syntaxin 3 in cone photoreceptors lacking BBS8. (A) Immunolocalization of M-opsin and peanut agglutinin (PNA) in retinal cross-sections of Cone-Bbs8−/− animals compared with littermate controls at P30. Scale bar: 20μm. (B) Retinal cross-sections showing mislocalized synatxin 3 (white arrows; STX3 in green), co-stained with peanut agglutinin (PNA, red), in cones lacking BBS8 (Cone-Bbs8−/−) compared with wild –type littermate controls at P30. Scale bar: 10μm.
