Figure 2.

We retrieved full GWAS test statistics from public data bases (Materials and Methods). For each disease/trait, we filtered out the SNPs with P > 1e−3. The enrichment of GWAS SNPs in placenta eQTLs was quantified with odds ratio (OR). Positive Log₂OR indicates the GWAS SNPs were enriched for placenta eQTLs, and negative Log₂OR indicates GWAS SNPs were depleted for placenta expressional quantitative trait loci. The GWAS information is detailed in Supplementary Material, Table S5. TC, total cholesterol; Asthma; HDL, high-density lipoprotein; LDL, low-density lipoprotein; TG, triglycerides; SCZ, psychiatric schizophrenia; CD, Crohn’s disease; Height, body height; BP_Sys, systolic blood pressure; UC, ulcerative colitis; AD, Alzheimer’s disease; BIP, psychiatric bipolar disorder; BMI, body mass index; COPD, chronic obstructive pulmonary disease; BP_Dia diastolic blood pressure; T2D, type 2 diabetes; ADHD, psychiatric attention-deficit hyperactivity disorder; CAD, coronary artery disease; MDD, psychiatric major depressive disorder.