Table 2.

Results of voxelwise analysis of connectivity variability between medial prefrontal cortex and other default mode network regions. C: citalopram, P: placebo, PC: placebo first, citalopram second, CP: citalopram first, placebo second. X, Y, and Z values represent MNI coordinates. Clusters defined at a voxelwise threshold of .001 uncorrected with a cluster-level threshold of .05 FDR corrected.

Region	Brodmann area	Cluster extent (voxels)	F	FDR-corrected p	X	Y	Z	Direction
Effect of drug condition
Precuneus	31	21	70.35	< .001	-2	-56	38	C > P
Posterior cingulate cortex	23	17	45.68	< .001	-2	-38	30	C > P
Effect of order
Angular gyrus	39	20	66.25	0.001	-46	-72	30	PC > CP
Precuneus	23	7	45.65	0.041	-4	-64	28	PC > CP
Angular gyrus	39	9	35.24	0.032	-40	-56	24	PC > CP
Drug X order interaction
Middle temporal gyrus	21	7	36.95	0.044	48	-50	16	-