Table 2.
The Associations of Grandmaternal and Child Birth Weight and Fetal Growth in the Aberdeen Maternity and Neonatal Databank-Study 1950-2015. Pearson Correlation Coefficients, Mean Group Values And Regression Coefficients And Their 95 % Confidence Intervals From Linear Regression Analyses Where All Continuous Variables Are Expressed in Standard Deviation Units.
Univariate analyses | Model 1a | Model 2b | Model 3c | Model 4d | |||||||
---|---|---|---|---|---|---|---|---|---|---|---|
Grandmaternal Birth Weight | No. | r= | P | B | 95 % CI | B | 95 % CI | B | 95 % CI | B | 95 % CI |
Child Birth Weight as Measured | |||||||||||
As Measured | 1457 | 0.19 | <0.001 | 0.18 | 0.13, 0.23 | 0.18 | 0.13, 0.23 | 0.12 | 0.07, 0.18 | 0.12 | 0.07, 0.18 |
Adjusted for sex and gestational age | 1280 | 0.18 | <0.001 | 0.17 | 0.11, 0.22 | 0.17 | 0.11, 0.22 | 0.12 | 0.06, 0.17 | 0.12 | 0.06, 0.17 |
Child Birth Weight Adjusted for sex and gestational age | |||||||||||
As Measured | 1426 | 0.19 | <0.001 | 0.19 | 0.13, 0.24 | 0.18 | 0.13, 0.23 | 0.12 | 0.07, 0.18 | 0.12 | 0.07, 0.18 |
Adjusted for sex and gestational age | 1252 | 0.18 | <0.001 | 0.18 | 0.13, 0.23 | 0.17 | 0.12, 0.23 | 0.12 | 0.07, 0.17 | 0.12 | 0.06, 0.18 |
B=unstandardized regression coefficient; CI=Confidence Interval; r=Pearson correlation coefficient; SD=Standard deviation
Regression model 1 is adjusted for child sex in the grandchild’s generation, year of delivery, maternal age at delivery, socioeconomic deprivation level of the family and parity in the grandmother’s, mother’s and child’s generation.
Model 2 includes model 1 covariates and maternal hypertensive disorders during pregnancy, pre-existing or gestational diabetes, labour type and maternal smoking during pregnancy in grandmaternal, maternal and child’s generations.
Model 3 is adjusted for model 2 covariates and also for birth weight in the intermediate generation.
Model 4 is adjusted for model 3 covariates and maternal height, body mass index and gestation of weight measurement during pregnancy.