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. Author manuscript; available in PMC: 2018 Dec 1.
Published in final edited form as: Am J Epidemiol. 2018 Jun 1;187(6):1165–1173. doi: 10.1093/aje/kwx340

Table 2.

The Associations of Grandmaternal and Child Birth Weight and Fetal Growth in the Aberdeen Maternity and Neonatal Databank-Study 1950-2015. Pearson Correlation Coefficients, Mean Group Values And Regression Coefficients And Their 95 % Confidence Intervals From Linear Regression Analyses Where All Continuous Variables Are Expressed in Standard Deviation Units.

Univariate analyses Model 1a Model 2b Model 3c Model 4d
Grandmaternal Birth Weight No. r= P B 95 % CI B 95 % CI B 95 % CI B 95 % CI
Child Birth Weight as Measured
As Measured 1457 0.19 <0.001 0.18 0.13, 0.23 0.18 0.13, 0.23 0.12 0.07, 0.18 0.12 0.07, 0.18
Adjusted for sex and gestational age 1280 0.18 <0.001 0.17 0.11, 0.22 0.17 0.11, 0.22 0.12 0.06, 0.17 0.12 0.06, 0.17
Child Birth Weight Adjusted for sex and gestational age
As Measured 1426 0.19 <0.001 0.19 0.13, 0.24 0.18 0.13, 0.23 0.12 0.07, 0.18 0.12 0.07, 0.18
Adjusted for sex and gestational age 1252 0.18 <0.001 0.18 0.13, 0.23 0.17 0.12, 0.23 0.12 0.07, 0.17 0.12 0.06, 0.18

B=unstandardized regression coefficient; CI=Confidence Interval; r=Pearson correlation coefficient; SD=Standard deviation

a

Regression model 1 is adjusted for child sex in the grandchild’s generation, year of delivery, maternal age at delivery, socioeconomic deprivation level of the family and parity in the grandmother’s, mother’s and child’s generation.

b

Model 2 includes model 1 covariates and maternal hypertensive disorders during pregnancy, pre-existing or gestational diabetes, labour type and maternal smoking during pregnancy in grandmaternal, maternal and child’s generations.

c

Model 3 is adjusted for model 2 covariates and also for birth weight in the intermediate generation.

d

Model 4 is adjusted for model 3 covariates and maternal height, body mass index and gestation of weight measurement during pregnancy.