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. Author manuscript; available in PMC: 2018 Aug 1.
Published in final edited form as: Endocr Relat Cancer. 2017 May 31;24(8):R275–R295. doi: 10.1530/ERC-17-0121

Figure 4. Overview of novel therapeutic strategies to disrupt select AR transcriptional complexes.

Figure 4

Polyamides inhibit the binding of transcription factors with chromatin. Specific inhibitors target enzymatic moieties of some coregulators. Peptides, peptidomimetics, and multivalent peptoid conjugates disrupt specific AR-coregulatory interactions.