Table 2. The input and output variables of the developed ANN model.

Input variable	Range	Mean ± SD
Age (yr)	17 – 61	32.4 ± 9.8
Body mass index (kgm-2)	11.7 – 30.1	20.5 ± 3.5
Male: Female	108: 28
CYP3A5 *1/*1:*1/*3:*3/*3	26:58:52
ABCB1 1236 CC:CT:TT	40:59:37
ABCB1 2677 GG:GA/GT:TT/AT/AA	15:51:70
ABCB1 3435 CC:CT:TT	31:65:40
Output variable	Range	Mean ± SD
Trough/dose	0.31-32.40	3.45 ± 4.45