Table 4. Patient and tumor characteristics according to the type of histological review (n = 341).
| Second Opinion N = 261 | Systematic Review N = 17 | Internal Network Review N = 63 | p-Valuea | |
|---|---|---|---|---|
| Age at diagnosis (years) | ||||
| Median (range) | 59 (2.06–101.62) | 63 (43–80) | 58 (18–92) | 0.4081 |
| Soft tissue | 197 (75.5%) | 14 (82.4%) | 48 (76.2%) | 0.8125 |
| Viscera | 64 (24.5%) | 3 (17.6%) | 15 (29.8%) | |
| Tumor size, mmb | ||||
| Median (range) | 40 (5–400) | 57 (15–160) | 40 (7–200) | 0.4481 |
| Localizationc | 0.1660 | |||
| Superficial | 81 (31.6%) | 2 (11.8%) | 18 (30.0%) | |
| Deep | 161 (62.9%) | 12 (70.6%) | 37 (61.7%) | |
| Superficial and deep | 14 (5.5%) | 3 (17.6%) | 5 (8.3%) | |
| Histological type | 0.3975 | |||
| Sarcoma | 53 (20.3%) | 3 (17.6%) | 8 (12.7%) | |
| GIST | 4 (1.5%) | 0 (0%) | 2 (3.2%) | |
| Desmoid tumor | 17 (6.5%) | 0 (0%) | 6 (9.5%) | |
| Intermediate malignant tumor | 12 (4.6%) | 1 (5.9%) | 3 (4.8%) | |
| Non-sarcoma malignant tumor | 58 (22.2%) | 8 (47.1%) | 19 (30.2%) | |
| Benign tumor | 117 (44.9%) | 5 (29.4%) | 25 (39.6%) | |
| Type of tumor sample | 0.1752 | |||
| Surgical biopsy | 52 (19.9%) | 2 (11.8%) | 8 (12.7%) | |
| Core needle biopsy | 27 (10.4%) | 4 (23.5%) | 4 (6.3%) | |
| Tumor resection | 182 (69.7%) | 11 (64.7%) | 51 (81.0%) | |
| IHC | 0.578 | |||
| Yes | 253 (96.9%) | 17 (100%) | 63 (100%) | |
| No | 8 (3.1%) | 0 (0%) | 0 (0%) | |
| Molecular biologyd | 0.963 | |||
| Yes | 46 (17.7%) | 3 (17.6%) | 10 (15.9%) | |
| No | 214 (82.3%) | 14 (82.4%) | 53 (84.1%) | |
| FISHe | 0.173 | |||
| Yes | 76 (29.2%) | 8 (47.1%) | 15 (23.8%) | |
| No | 184 (70.8%) | 9 (52.9%) | 48 (76.2%) |
ap-values were calculated using Chi-square tests (except for age and tumor size, for which a Mann-Whitney-Wilcoxon test was used).
bMissing data n = 65.
cMissing data n = 8.
dMissing data n = 1.
eMissing data n = 1.
Abbreviations: IHC: Immunohistochemistry; FISH: Fluorescent in situ hybridization