Skip to main content
. 2018 Mar 30;23(1):10–17. doi: 10.15430/JCP.2018.23.1.10

Figure 2.

Figure 2

Esculetin dose-dependently induces apoptosis and cell cycle arrest of PC3, DU145, and LNCaP cells. The cells were treated with 25 μM, 50 μM, and 150 μM esculetin for 48 hours, then apoptosis rates and cell cycle analyses were determined by image-based cytometer. Live, dead, and apoptotic populations of (A) PC3, (B) DU145, and (C) LNCaP cells. Esculetin administration caused cell cycle arrest at G1 phase in (D) PC3, (E) DU145, and (F) LNCaP cells. *P < 0.05 vs. untreated (Ut), **P < 0.01 vs. Ut and 25 μM esculetin, ***P < 0.01 vs. Ut, 25 and 75 μM esculetin groups.