Table 1. Demographics and ocular data including macular ganglion cell layer plus inner plexiform layer (mGCIPL), mGCIPL plus nerve fiber layer (mGCC) and total retinal layer (TRL) measurements by swept source optical coherence tomography (SS-OCT) wide scan and standard macula scan, and circumpapillary retinal nerve fiber layer (cpRNFL) measurements by SS-OCT wide scan and standard disc scan of normal subjects and glaucoma patients.
| Total | Normal | Glaucoma | P value | ||
|---|---|---|---|---|---|
| N | 122 | 62 | 60 | ||
| Age (years)* | 56.60 ± 13.73 | 55.42 ± 14.64 | 57.80 ± 12.73 | 0.550 | |
| Gender (F : M)† | 64 : 58 | 35 : 27 | 29 : 31 | 0.806 | |
| IOP (mmHg)* | 14.84±3.11 | 15.53 ± 2.84 | 14.12 ± 3.23 | 0.470 | |
| MD (dB) * | -3.61 ± 5.42 | 0.00 ± 0.67 | -5.26 ± 5.83 | <0.001 | |
| PSD (dB) * | 3.48 ± 2.86 | 1.90 ± 0.60 | 4.25 ± 3.17 | <0.001 | |
| Macular thickness (μm) | |||||
| Wide scan* | mGCIPL (Total) | 72.40 ± 5.86 | 64.16 ± 7.85 | <0.001 | |
| mGCC (Total) | 109.80 ± 8.04 | 97.35 ± 12.27 | <0.001 | ||
| TRL (Total) | 278.17 ± 15.86 | 267.58 ± 15.77 | <0.001 | ||
| Standard macula scan* | mGCIPL (Total) | 71.65 ± 5.63 | 64.34 ± 6.66 | <0.001 | |
| mGCC (Total) | 107.81 ± 8.06 | 95.56 ± 11.89 | <0.001 | ||
| TRL (Total) | 278.18 ± 15.96 | 267.48 ± 15.77 | <0.001 | ||
| cpRNFL thickness (μm) | |||||
| Wide scan* | cpRNFL | Total | 109.39 ± 9.33 | 86.44 ± 17.06 | <0.001 |
| Temp | 82.61 ± 12.87 | 72.15 ± 14.65 | <0.001 | ||
| Sup | 132.14 ± 14.32 | 102.05 ± 25.04 | <0.001 | ||
| Nas | 82.87±12.58 | 69.17 ± 16.10 | <0.001 | ||
| Inf | 140.43 ± 17.62 | 102.39 ± 27.65 | <0.001 | ||
| Standard disc scan* | cpRNFL | Total | 109.49 ± 9.46 | 86.48 ± 15.68 | <0.001 |
| Temp | 81.90 ± 12.34 | 70.08 ± 13.69 | <0.001 | ||
| Sup | 134.23 ± 14.48 | 103.98 ± 23.84 | <0.001 | ||
| Nas | 82.26±12.41 | 69.04 ± 14.45 | <0.001 | ||
| Inf | 141.23 ± 16.97 | 102.88 ± 25.92 | <0.001 | ||
Values are presented as weighted mean ± standard deviation (SD),
*Independent t-test;
†Chi-square test. Abbreviations: IOP = intraocular pressure; MD = Mean deviation; PSD = pattern standard deviation; dB = decibels; mGCIPL = ganglion cell layer plus inner plexiform layer; mGCC = mGCIPL plus nerve fiber layer; TRL = total retinal layer; cpRNFL = circumpapillary retinal nerve fiber layer; Temp = Temporal; Sup = Superior; Nas = Nasal; Inf = Inferior