Table 2. Markers of lipid peroxidation and antioxidant enzyme activities in the blood of patients.
ARC | ARC and HT | ARC, HT, and DM | P value | |
---|---|---|---|---|
Number of subjects, n (%) | 41 (32%) | 69 (53.0%) | 20 (15%) | |
XO (U/L) | 6.2±0.9 | 9.4±1.3 | 11.9±0.9 | <0.01 |
MPO (U/L) | 52.4±6.3 | 77.3±8.4 | 89.5±5.0 | <0.01 |
LLF (RFU/mL) | 48.4±5.2 | 79.7±11.0 | 92.3±4.5 | <0.01 |
MDA (µmol/L) | 4.6±0.8 | 6.6±0.5 | 8.0±0.6 | <0.01 |
SH groups (µmol/L) | 501.4±45.6 | 400.6±34.6 | 312.7±40.6 | <0.01 |
FRAP (µmol/L) | 774.2±100.1 | 613.9±43.9 | 575.9±67.6 | <0.01 |
GPx (U/L) | 185.2±12.5 | 235.2±19.7 | 287.7±11.9 | <0.01 |
SOD (U/L) | 38.7±1.2 | 29.9±3.0 | 24.1±2.7 | <0.01 |
Data are reported as means±SD. ARC: age-related cataract; HT: hypertension; DM: diabetes mellitus; XO: xanthine oxidase; MPO: myeloperoxidase; LLF: lipofuscin-like fluorophores; MDA: malondialdehyde; SH: thiol; FRAP: ferric reducing/antioxidant power assay; GPx: glutathione peroxidase; SOD: superoxide dismutase. Statistical analysis was done with ANOVA the post hoc Tukey's test.