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. 2018 Apr 5;13(4):e0195441. doi: 10.1371/journal.pone.0195441

Table 1. Individuals (%) at high risk of developing lung cancer using the ENSE survey of 2011–2012 and extrapolation into absolute figures for the target population at national level*.

Population at risk in the ENSE sample Target population at national level*
N NELSON criteria NLST
criteria
Total population NELSON criteria NLST criteria
% (95% CI) % (95% CI) n n N
General population**
    All 21,006 6.6 (6.2; 6.9) 4.9 (4.6; 5.2) 39,441,665 2,653,744 2,003,483
    Men 9,648 9.7 (9.1; 10.3) 7.9 (7.4; 8.5) 19,234,370 1,862,034 1,523,120
    Women 11,358 3.9 (3.6; 4.3) 2.4 (2.1; 2.7) 20,207,295 791,710 480,364
Ever-smoker population***
    All 9,496 14.5 (13.8; 15.2) 10.9 (10.3; 11.5) 18,122,937 2,653,744 2,003,483
    Men 5,727 16.3 (15.4; 17.3) 13.3 (12.5; 14.2) 11,417,417 1,862,034 1,523,120
    Women 3,769 11.8 (10.8; 12.8) 7.2 (6.3; 8.0) 6,705,520 791,710 480,364

* Target population using Spanish population census data of 2014 (www.ine.es).

** All population was used in the denominator for the computation of the prevalence.

*** Ever-smoker population was used in the denominator for the computation of the prevalence.

NELSON eligibility criteria: Age: 50–74 years. Smoking history: >15 cigarettes/day during >25 years; or >10 cigarettes/day during >30 years; if former smokers, quitting time ≤10 years. Trial registration number: ISRCTN63545820.

NLST eligibility criteria: Age: 55–74 years. Smoking history: pack-years ≥30 years; if former smokers, quitting time ≤15 years. Trial registration number: NCT00047385

CI: confidence interval.