Table 3. Clinical characteristics of HIV positive children (<15 years of age) [N = 1159] at enrolment into Anti-Retroviral therapy Care (ART) care in Mingalardon Specialist Hospital in Yangon between 2006 and 2016.
Clinical characteristics | Overall | 2006–2009 | 2010–2013 | 2014–2016 | ||||
---|---|---|---|---|---|---|---|---|
Number | % (column) | Number | % (row) | Number | % (row) | Number | % (row) | |
WHO Staging | ||||||||
- Stage 1 | 231 | 19.9 | 1 | 0.4 | 11 | 4.8 | 219 | 94.8 |
- Stage 2 | 109 | 9.4 | 4 | 3.7 | 34 | 31.2 | 71 | 65.1 |
- Stage 3 | 623 | 53.8 | 111 | 17.8 | 254 | 40.8 | 258 | 41.4 |
- Stage 4 | 196 | 16.9 | 39 | 19.9 | 104 | 53.1 | 53 | 27.0 |
CD4 Count baseline | ||||||||
- <50 cells/mm3 | 199 | 17.2 | 38 | 19.1 | 76 | 38.2 | 85 | 42.7 |
- 50–200 cells/mm3 | 246 | 21.2 | 29 | 11.8 | 99 | 40.2 | 118 | 48.0 |
- 201–350 cells/mm3 | 147 | 12.7 | 23 | 15.6 | 64 | 43.5 | 60 | 40.8 |
- 351–500 cells/mm3 | 120 | 10.4 | 19 | 15.8 | 35 | 29.2 | 66 | 55.0 |
- >500 cells/mm3 | 384 | 33.1 | 34 | 8.9 | 109 | 28.4 | 241 | 62.8 |
- Missing | 63 | 5.4 | 12 | 19.0 | 20 | 31.7 | 31 | 49.2 |
TB | ||||||||
- Yes | 674 | 58.2 | 121 | 18.0 | 263 | 39.0 | 290 | 43.0 |
- No | 485 | 41.8 | 34 | 7.0 | 140 | 28.9 | 311 | 64.1 |
TB status during ART treatment | ||||||||
- Pulmonary TB (Smear +) | 4 | 0.6 | 1 | 25.0 | 0 | 0.0 | 3 | 75.0 |
- Pulmonary TB (smear -) | 116 | 17.2 | 60 | 51.7 | 48 | 41.4 | 8 | 6.9 |
- Extra Pulmonary TB | 51 | 7.6 | 8 | 15.7 | 13 | 25.5 | 30 | 58.8 |
- Pulmonary TB | 465 | 69 | 43 | 9.2 | 181 | 38.9 | 241 | 51.8 |
- Missing | 38 | 5.6 | 9 | 23.7 | 21 | 55.3 | 8 | 21.1 |
Prophylaxis for OI | ||||||||
- Yes | 960 | 82.8 | 143 | 14.9 | 345 | 35.9 | 472 | 49.2 |
- No | 199 | 17.2 | 12 | 13.4 | 58 | 29.1 | 129 | 64.8 |
Outcome of ART patients | ||||||||
- Alive and on ART | 993 | 85.7 | 116 | 11.7 | 341 | 34.3 | 536 | 54.0 |
- Death | 57 | 4.9 | 10 | 17.5 | 29 | 50.9 | 18 | 31.6 |
- Lost to follow up | 55 | 4.7 | 6 | 10.9 | 18 | 32.7 | 31 | 56.4 |
- Transfer out | 54 | 4.7 | 23 | 42.6 | 15 | 27.8 | 16 | 29.6 |
Regime of ART patients | ||||||||
-NNRTI based regime | 1092 | 94.2 | 137 | 12.5 | 380 | 34.8 | 575 | 52.7 |
- PI based regime | 67 | 5.8 | 18 | 26.9 | 23 | 34.3 | 26 | 38.8 |
NNRTI-Non-Nucleoside reverse-transcriptase inhibitor; PI-Protease inhibitor; OI-opportunistic infection; CD4-CD4 +T lymphocyte count.